Biomedical Advanced Research and Development Authority (BARDA)

  • BARDA Broad Agency Announcement rolling until 9/25/2028 
    BARDA is soliciting proposals for the advanced R&D of medical countermeasures for chemical, biological, radiological and nuclear agents; the ever-present and ever -evolving threat of pandemic influenza; and the re-emergence and emergence of infectious diseases that threaten the U.S. civilian population. 

Department of Defense

  • FY2026 Department of Defense Multidisciplinary Research Program of the University Research Initiative (MURI) optional white papers due 5/2/2025, full proposals due 9/5/2025              
    DoD's MURI program addresses high-risk basic research and attempts to understand or achieve something that has never been done before. MURI is sponsored by the Office of Naval Research (ONR), the Army Research Office (ARO), and the Air Force Office of Scientific Research (AFOSR), each of which has specific research topics listed in the NOFO.
  • Artificial Intelligence Integration Center (AI2C) Broad Agency Announcement rolling until 6/16/2025              
    The Army Artificial Intelligence Integration Center (AI2C) is seeking artificial intelligence research and development whitepapers and proposals in support of new technologies and translational research-based approaches that support the identification, alignment, and exploitation of basic, applied, and advanced research and technology. Areas of interest include Autonomous Platforms, AI/ML, AI/ML decision support, Human-AI Integration, Synthetic Environments, Distributed AI, Underpinning Methodologies, and Special Topics.
  • DARPA Tactical Technology Office (TTO) Office-Wide Broad Agency Announcement rolling until 6/20/2025              
    TTO is soliciting innovative executive summaries and proposals that enhance the nation’s ability to rapidly build, adapt and sustain force structures with the following focus areas: Platform Innovation, Missionized Autonomy, Managing Complexity, Freedom’s Forge 2.0, and Disruptive Emergent Technology.
  • Congressionally Directed Medical Research Programs FY25 Preannouncements
    The CDMRP fills research gaps by funding high impact, high risk and high gain projects that other agencies may not venture to fund. The CDMRP strives to transform health care for Service Members and the American public through innovative and impactful research.
  • DARPA Biological Technologies Office (BTO) Broad Agency Announcement rolling until 9/10/2025                  
    BTO is interested in submissions related to the following topic areas: Biological technology topic areas that fit the national security scope of BTO’s mission; Machine Learning (ML) and Artificial Intelligence (AI); Human Performance; Materials, Sensors, Processing; Ecosystem and Environmental; Biosecurity and Biosafety; and Biomedical and Biodefense.
  • DARPA Defense Sciences Office (DSO) Office-wide Broad Agency Announcement rolling until 9/26/2025        
    The mission of the Defense Advanced Research Projects Agency (DARPA) Defense Sciences Office (DSO) is to identify and create the next generation of scientific discovery to fuel innovation throughout the Agency and beyond. Technical thrust areas are Novel Materials & Structures, Sensing & Measurement, Computation & Processing, Enabling Operations, Collective Intelligence & Emerging Threats.
  • FY25 Long Range Broad Agency Announcement (BAA) for Navy and Marine Corps Science and Technology rolling until 9/30/2025  
    ONR technology areas of interest are listed on the ONR Technology and Research site. Potential offerors are urged to check the website throughout the year for updates to technology areas. 
  • DARPA Information Innovation Office (I2O) Broad Agency Announcement rolling until 10/29/2025              
    This Broad Agency Announcement (BAA) seeks revolutionary research ideas for topics not being addressed by ongoing I2O programs or other published solicitations. The Information Innovation Office (I2O) creates groundbreaking science and develops transformational capabilities in the informational and computational spheres to surprise adversaries and maintain enduring advantages for national security. I2O programs address elements of four key thrust areas: Proficient artificial intelligence (AI); Resilient, adaptable, and secure systems; Advantage in cyber operations; and Confidence in the information domain.
  • AFRL Geospatial Intelligence Processing and Exploitation (GeoPEX) Broad Agency Announcement rolling until 9/30/2026              
    The Air Force Research Laboratory seeks white papers for research, development, integration, test and evaluation of technologies/techniques to provide geospatial intelligence.
  • USAMRDC FY23-FY27 Broad Agency Announcement for Extramural Medical Research rolling until 9/30/2027              
    The USAMRDC’s mission is to provide solutions to medical problems of importance to the American Service Member at home and abroad, as well as to the general public at large. The BAA includes the Military Infectious Diseases Research Program, Combat Casualty Care Research Program, Military Operational Medicine Research Program. 
  • DEVCOM Army Research Laboratory Broad Agency Announcement for Foundational Research rolling until 11/20/2027                 
    The DEVCOM ARL Broad Agency Announcement for Foundational Research is a competitive solicitation procedure used to obtain proposals for basic research that support ARL’s mission of operationalizing science. Research topics are listed on ARL's website.
  • DEVCOM Analysis Center Broad Agency Announcement for Applied Research rolling until 1/4/2028       
    The DEVCOM ARL Broad Agency Announcement for Applied Research is a competitive solicitation procedure used to obtain proposals for applied research that support ARL’s mission of operationalizing science. Research topics are listed on ARL's website.
  • Defense Threat Reduction Agency (DTRA) Biological Threat Reduction with Global Partners Broad Agency Announcement (BAA) rolling until 4/28/29              
    BTRP supports international health security efforts to address diseases caused by U.S. Biological Select Agents, pathogens of pandemic potential, and emerging (and reemerging) infectious diseases. BTRP is interested in collaborative engagements with foreign partners in any of the following: countries of the Former Soviet Union (FSU), Africa, Southeast Asia, and Middle East/South Asia.
  • Defense Threat Reduction Agency (DTRA) Fundamental Research to Counter Weapons of Mass Destruction rolling until 9/30/34              
    DTRA seeks to identify, adopt, and adapt emerging, existing, and revolutionary sciences that may demonstrate high payoff potential to Counter-WMD (C-WMD) threats. Thrust Area 1— Fundamental Science for Chemical and Biological Defense: Fundamental science for chemical and biological (CB) defense includes science and technology research that advances knowledge in physical and life sciences to defend and counter chemical and biological WMD that could be used against our Nation’s warfighters.
  • Research Interests of the Air Force Office of Scientific Research open until closed   
    Funds basic research in the areas of Engineering and Complex Systems, Information and Networks, Physical Sciences, Chemistry and Biological Sciences.

Department of Energy

  • FY 2025 Continuation of Solicitation for the Office of Science Financial Assistance Program rolling until 9/30/2025
    The Office of Science annual solicitation for all research areas: Advanced Scientific Computing Research, Basic Energy Sciences, Biological and Environmental Research, Fusion Energy Sciences, High Energy Physics, Nuclear Physics, Isotope R&D and Production, and Accelerator R&D and Production.
  • ARPA-E Spurring Projects to Advance Energy Research and Knowledge Swiftly (SPARKS) open until closed
    This Funding Opportunity Announcement (FOA) provides a continuing opportunity for the rapid support of early stage applied research to explore innovative new concepts with the potential for transformational and disruptive changes in energy technology. The categories are Grid, Transportation, Building & Construction, Electricity Generation & Storage, Carbon Capture, Sequestration and Utilization, Industrial Efficiency and Utilization.

National Aeronautics and Space Administration

National Institutes of Health

National Institute of Standards and Technology

National Science Foundation

  • Expeditions in Computing (Expeditions) due 7/9/2025  
    Supports long-term, multi-institutional research with the potential to transform computer and information science and engineering.
  • CyberCorps Scholarship for Service (SFS) due 7/15/2025  
    Supports scholarships in cybersecurity that require a service obligation following graduation equivalent to the length of the scholarship
  • Accountable Institutions and Behavior (AIB) due 8/15/2025  
    Supports theoretically motivated research on governance-related attitudes, behavior and institutions in democratic and non-democratic settings, in areas such as preference formation and expression, voting and elections, and decision making and public policy.
  • Security and Preparedness due 8/15/2025  
    Supports research and research infrastructure on issues related to global and national security, including international conflict and dispute resolution, domestic political instability and civil war, and security implications of natural hazards and stressors.
  • Smart and Connected Communities (S&CC) due 9/8/2025  
    Supports interdisciplinary, high-risk research that integrates intelligent technologies with natural and built environments to tackle critical challenges and enhance the quality of life in communities through collaboration with stakeholders.
  • Community Infrastructure for Research in Computer and Information Science and Engineering (CIRC) due 9/12/2025  
    This program drives discovery and learning in the core disciplines of the three participating CISE divisions [Computing and Communication Foundations (CCF), Computer and Network Systems (CNS), and Information and Intelligent Systems (IIS)] by funding the creation and enhancement of world-class research infrastructure.
  • Security, Privacy, and Trust in Cyberspace (SaTC 2.0) due 9/29/2025  
    Supports interdisciplinary research and education to develop a secure, resilient and trustworthy global cyber ecosystem by addressing vulnerabilities, improving trust in cyber systems and cultivating a well-trained cybersecurity workforce.
  • Mathematical Foundations of Artificial Intelligence (MFAI) due 10/10/2025  
    Supports research collaborations between mathematicians, statisticians, computer scientists, engineers and social behavior scientists to establish innovative and principled design and analysis approaches for AI technology.
  • Major Research Instrumentation (MRI) due 11/14/2025  
    Supports requests for up to $4 million from NSF for the development or acquisition of multi-user research instruments that are critical to the advancement of science and engineering.
  • Cybersecurity Innovation for Cyberinfrastructure (CICI) due 1/21/2026  
    Supports the development and integration of advanced cybersecurity solutions to improve scientific cyberinfrastructure's security, resilience and usability, enabling secure and reproducible data-driven discoveries across various research fields.
  • The Algorithms for Modern Power Systems (AMPS) due 2/9/2026  
    Supports research to develop mathematical and statistical algorithms that improve the security, reliability and efficiency of the modern power grid.
  • Scholarships in Science, Technology, Engineering, and Mathematics Program (S-STEM) due 3/3/2026   
    Supports institutions of higher education to fund scholarships for academically talented low-income STEM majors and to study and implement a program of activities that support their recruitment, retention and graduation. This is a limited submission opportunity.
  • Cyber-Physical Systems (CPS) due per solicitation  
    Supports research on engineered systems with a seamless integration of cyber and physical components, such as computation, control, networking, learning, autonomy, security, privacy and verification, for a range of application domains.
  • Advanced Manufacturing (AM) accepted anytime  
    Supports fundamental manufacturing research that addresses issues related to national prosperity and security and has the potential to contribute to the revitalization of American manufacturing.
  • Communications, Circuits, and Sensing-Systems (CCSS) accepted anytime  
    Supports research on circuit and system hardware and signal processing techniques in the following areas: radio-frequency circuits and antennas for communications and sensing; communication systems and signal processing; and dynamic bio-sensing systems.
  • Computational and Data-Enabled Science and Engineering (CDS&E) due per solicitation  
    Supports research that uses new computational and data science approaches to advance knowledge and accelerate discovery in science and engineering.
  • Crosscutting Activities in Materials Research (XC) accepted anytime 
    Supports crosscutting activities in the Division of Materials Research and across NSF that emphasize diversity and inclusion, international collaboration and education. Activities such as institutes, workshops and conferences may be supported.
  • Division of Materials Research: Topical Materials Research Programs (DMR-TMRP) accepted anytime
    Supports fundamental materials research and education in the following areas: biomaterials, ceramics, condensed matter physics, electronic and photonic materials, metals and metallic nanostructures, polymers, and solid state and materials chemistry.
  • ECosystem for Leading Innovation in Plasma Science and Engineering (ECLIPSE) due per solicitation  
    Supports translational research and workforce development at the interface of fundamental plasma science and technological innovation.
  • Energy, Power, Control, and Networks (EPCN) accepted anytime
    Supports research in modeling, optimization, learning, adaptation and control of networked multi-agent systems; higher-level 
  • Facilities for Atmospheric Research and Education (FARE) accepted anytime
    To facilitate fundamental research in the atmospheric sciences, the Division of Atmospheric and Geospace Sciences (AGS) supports state-of-the-art instruments and facilities through the Facilities for Atmospheric Research and Education (FARE) Program.  The FARE Program includes the Lower Atmosphere Observing Facilities (LAOF) and the Community Instruments and Facilities (CIF).
  • Infrastructure, Systems and People accepted anytime
    Supports fundamental research on the design, optimization, sustainability and resilience of infrastructure systems during normal operation and extreme events, such as natural hazards, to serve community needs.
  • Windows on the Universe: The Era of Multi-Messenger Astrophysics (WoU-MMA) due per solicitation  
    Supports research to advance the interoperability of studies using electromagnetic waves, high-energy particles including neutrinos and cosmic rays, and gravitational waves to realize integrated, multi-messenger astrophysical explorations of the universe.